Patients are seeking direction, guidance and recommendations concerning marijuana. With Ohio’s new law and growing acceptance of the plant, physicians must be ready to respond with well-reasoned, scientifically sound answers, many of which are not yet taught in medical school. Education is the key. 1.) The compounds in cannabis act upon the endocannabinoid system, a physiologic system integral to health and healing. “Modulating endocannabinoid system activity may have therape